| 标题： | 反复妊娠丢失的男性因素评估与管理中国专家共识 |
| title： | Chinese experts’ consensus on the assessment and management of male factors in recurrent pregnancy loss |
| 版本： | 原创版 |
| version： | Original |
| 分类： | 专家共识 |
| classification： | Experts consensus |
| 领域： | 诊疗 |
| field： | Diagnosis and Treatment |
| 国家和地区： | 中国 |
| Country and region： | China |
| 指南使用者： | 从事生殖医学、男科学的专业医务人员 |
| Guide users： | medical professionals engaged in reproductive medicine and andrology |
| 证据分级方法： | GRADE |
| Evidence grading method： | GRADE |
| 制定单位： | 中国医师协会生殖医学专业委员会生殖男科学组反复妊娠丢失的男性因素评估与管理中国专家共识编写组 |
| Formulating unit： | Chinese Expert Consensus Compilation Group for Assessment and Management of Male Factors in Recurrent Pregnancy Loss, Reproductive Andrology Group, Reproductive Medicine Professional Committee of Chinese Medical Doctor Association |
| 注册时间： | 2022-06-14 |
| Registration time： | |
| 注册编号： | IPGRP-2022CN334 |
| Registration number： | |
| 指南制订的目的： | 反复妊娠丢失（recurrent pregnancy loss, RPL）是不孕症之外，另一种临床最常见的生育问题之一，其病因较为复杂，是一个涉及多种因素参与的复杂疾病。传统观念认为女性因素在其发生过程中起着决定性作用，随着近年来研究的不断深入，越来越多的证据证明男性因素同样不容忽视。有鉴于此，中国医师协会生殖医学专业委员会生殖男科学组组织了生殖男科领域的专家，从染色体异常、精液参数、精子非整倍性以及一些基因的多态性和精子的表观遗传等方面的评估和临床管理进行了深入的探讨。本共识可谓从事生殖医学、男科学的专业医务人员提供专家咨询和建议。 |
| Purpose of the guideline： | In addition to infertility, recurrent pregnancy loss(RPL) is one of the most common clinical fertility problems, which is a complex disease involving many factors with diverse causes. The traditional beliefs hold that female factors play a decisive role in its occurrence. With the deepening of research in recent years, increasing evidences have also established that male factors also play a crucial role in RPL. Therefore, the Reproductive Andrology Group of the Professional Committee of Reproductive Medicine of the Chinese Medical Doctor Association organized experts in the field of reproductive andrology to conduct in-depth discussion on the assessment and clinical management of male factors, including chromosomal abnormalities, semen parameters, sperm aneuploidy, polymorphisms of some genes and epigenetic inheritance of sperm, etc. This consensus can provide expert consultation and advice for medical professionals engaged in reproductive medicine and andrology. |
