| 标题： | 抗菌药物防治肝性脑病多学科专家共识 |
| title： | Multidisciplinary consensus on hepatic encephalopathy prevention and treatment by antibacterial drugs |
| 版本： | 原创版 |
| version： | Original |
| 分类： | 专家共识 |
| classification： | Experts consensus |
| 领域： | 综合 |
| field： | Comprehensive guideline |
| 国家和地区： | 中国 |
| Country and region： | China |
| 指南使用者： | 临床医生 |
| Guide users： | Clinicians |
| 证据分级方法： | GRADE分级 |
| Evidence grading method： | GRADE |
| 制定单位： | 抗菌药物防治肝性脑病多学科专家组 |
| Formulating unit： | Multidisciplinary Task Force for hepatic encephalopathy prevention and treatment by antibacterial drugs |
| 注册时间： | 2022-09-15 |
| Registration time： | |
| 注册编号： | PREPARE-2022CN601 |
| Registration number： | |
| 指南制订的目的： | 肝性脑病（hepatic encephalopathy，HE）诱发因素多与感染相关，即使没有明显感染灶，肠道细菌移位、内毒素水平升高也可导致体内炎症状态。因此，HE的治疗原则为及时清除诱因、消除体内炎症，调控肠道菌群、恢复肠道稳态。本共识就利福霉素、氨基糖苷类、硝基咪唑类等抗菌药物和肠道微生态制剂在HE管理中的临床应用给予推荐意见，为抗菌药物防治HE提供临床指导。 |
| Purpose of the guideline： | Hepatic encephalopathy (HE) is mostly induced by infection. Internal inflammation can be caused by intestinal bacterial translocation or elevated endotoxin levels, even without evident infectious lesions. Therefore, the treatment principals of HE are supposed to be, timely removal of triggers, elimination of internal inflammation, regulation of intestinal flora, and restoration of intestinal homeostasis. This article is to provide recommended suggestions for clinical usage of antibacterial drugs and intestinal microbiota preparations including rifamycins, minoglycosides and nitroimidazoles in management of HE. |
最新注册
