Expert consensus on early anticoagulation of adult COVID-19 infection in emergency department

Title: Expert consensus on early anticoagulation of adult COVID-19 infection in emergency department
Edition: Original
Classification: Experts consensus
Field: Diagnosis and Treatment
Countries and regions: China
Guidelines users: Emergency physician who treats patients with COVID-19
Evidence classification method: Evidence level and description Low level evidence: future research is likely to have a significant impact on the current evaluation results, which could potentially alter the current recommendations. Moderate level of evidence: future research may have a significant impact on current evaluation results, which may alter current recommendations. High-level evidence: future research is almost impossible to change the current evaluation results.
Development unit: Emergency Medicine Branch of the Chinese Medical Association, Emergency Medicine Branch of the Shanghai Medical Association
Registration time: 2023-08-25
Registration number: PREPARE-2023CN631
Purpose of the guideline: In addition to respiratory symptoms, COVID-19 patients can also suffer from coagulation, cardiovascular, digestive, urinary, immune and other system injuries, and even rapid onset multiple organ dysfunction syndrome. Previous studies have shown that anticoagulant therapy can significantly improve tissue perfusion and protect multiple organ function when D-dimer slightly rises, which is one of the important strategies to block multiple organ injury in patients with COVID-19. The state of emergency treatment of COVID-19 patients can be divided into early onset and mid late onset. However, for emergency physicians, the first medical contact of patients, regardless of the stage of the disease, belongs to early stage (early disease or early treatment). Active and reasonable anticoagulation should be carried out according to the disease state to block multiple organ damage as soon as possible. This consensus is intended to provide basis for how to anticoagulate in COVID-19 patients in the ED.