| Title： | Chinese guidelines for the management of cerebral venous thrombosis during pregnancy and perinatal period |
| Edition： | Original |
| Classification： | Standard guideline |
| Field： | Comprehensive guideline |
| Countries and regions： | China |
| Guidelines users： | Clinicians |
| Evidence classification method： | The evidence grading of treatment measures is divided into four levels, with A representing the highest level and D the lowest: A level (highest): Meta-analysis or systematic review based on multiple randomized controlled trials; multiple high-quality randomized controlled trials or one adequately powered randomized controlled trial B level (high): Based on at least one high-quality randomized controlled trial C level (moderate): Based on well-designed non-randomized control studies, cohort studies, or case-control studies D level (low): Based on series of case analyses without contemporaneous controls or expert opinion The evidence grading of diagnostic measures is also divided into four levels, with A being the highest and D the lowest: A level (highest): Based on one or more prospective cohort studies with sufficient sample size, using a reference ("gold") standard and blinded assessment (high quality) B level (high): Based on at least one prospective cohort study or well-designed retrospective case-control study using a reference ("gold") standard and blinded assessment C level (moderate): Based on retrospective, non-blinded comparative studies D level (lowest): Based on serial case series analysis or expert opinion without contemporaneous control. |
| Development unit： | Xuanwu Hospital, Capital Medical University |
| Registration time: | 2024-08-13 |
| Registration number： | PREPARE-2024CN222 |
| Purpose of the guideline: | This guideline aims to offer evidence-based recommendations for Chinese clinicians regarding the diagnosis, treatment, and prevention of cerebral venous thrombosis (CVT) during pregnancy. The objectives include increasing awareness and diagnostic accuracy of CVT during pregnancy, standardizing the diagnostic process to minimize misdiagnosis, guiding the development of personalized treatment plans to reduce maternal and fetal complications and mortality, as well as providing preventive strategies to lower the risk of CVT. |
