guideline for neonatal respiratory distress syndrome

Title: guideline for neonatal respiratory distress syndrome
Edition: Original
Classification: Standard guideline
Field: Diagnosis and Treatment
Countries and regions: China
Guidelines users: Working referring to neonates, including neonatologists, neonatal surgeon, nurse, et al.
Evidence classification method: GRADE
Development unit: Children's hospital of Chongqing Medical University
Registration time: 2023-02-05
Registration number: PREPARE-2023CN062
Purpose of the guideline: Acute respiratory distress syndrome (ARDS) is one leading cause of respiratory mortality and morbidity, which is firstly reported by Ashbaugh and colleagues in 1967.  Since then, the diagnostic criteria of adult and pediatric ARDS are defined in the Berlin Conference and Pediatric Acute Lung Injury Consensus Conference (PALICC), respectively. However, the two criteria do not cover neonatal perinatal considerations. In 2017, the international neonatal ARDS (NARDS) collaborative group provides the first consensus definition of NARDS (Montreux definition) during the first phase of NARDS project. There are consistent themes in the definition of NARDS when compared with adult and pediatric ARDS which stem from similarities in pathophysiology and historical features. Our previous study showed that bronchopulmonary dysplasia (BPD) and/or death was observed in 213 (21.2%) infants, consisting 104 (10.3%) BPD and 126 (12.6%) deaths. The incidence of ROP, NEC, Airleak, LOS, PVL, IVH and hsPDA were 6.8%、6.1%,7%,9.3%,11.8%,26.6% and 39.1%. However, no guidelines for neonatal ARDS. Therefore, we aimed to formulate a guideline to prevention, diagnosis with differentially diagnosis, treatment for neonatal ARDS.