Expert Consensus on PARPi Interaction Management

Title: Expert Consensus on PARPi Interaction Management
Edition: Original
Classification: Experts consensus
Field: Administration
Countries and regions: China
Guidelines users:
Evidence classification method: Rating system were determined by this expert group
Development unit: Zhejiang Provincial People's Hospital
Registration time: 2022-09-12
Registration number: PREPARE-2022CN596
Purpose of the guideline: Most PARPi are metabolized by liver enzymes, and there are extensive drug interactions with other drugs, which are easy to be ignored in clinical use, resulting in increased toxicity or decreased efficacy. This consensus systematically summarizes the interaction of PARPi listed in China and forms relevant recommendations to provide reference for the safe and rational use of PARPi in clinic.